Cicatricial effect of Libidibia ferrea L. orabase formulation on traumatic ulcers oral in rats

The aim of this study was to evaluate the healing effect an orabase ointment based on Libidibia ferrea L. induced mouth ulcers in rats. This is experimental "in vivo", descriptive, quantitative using model animals were divided into 3 groups: Group I (test), II (negative control) and III (positive control), evaluated periods 1, 5 10 days after ulcerative induction. Regarding diameter ulcers, positive control group did not show a significant difference between times tested (p=0.994). In intergroup comparison, analysis day 5, diameters Jucá significantly smaller compared other groups (p=0.005). weight animals, all increased or maintained their at end ten-day period experiment. As for histopathological pattern, there (p=0.002) groups, with better result seen test group. There reduction treated when confirming activity proposed herbal formulation.